In this study, a wire/wireless communication system transmitting the operation data of engine from the ER (Engine Room) to the engine controller of ECR(Engine Control Room) has been developed through the communication of ISM(Industrial Science Medical) Band for the test operation environment improvement of medium speed engine. This wire/wireless communication system is composed of the RTU (Remote Terminal Unit) gathering and transmitting engine data as well as the MCU (Master Control Unit) receiving engine status information from the RTU to be sent to the engine controller (PLC). Through this study, a trial product of RTU and MCU has been manufactured. A test bench that has made temperature, pressure and pick-up sensor into a module for the local test of prototype was produced a test bench. In addition, at the same time save the data to a Web server and the smart phone real-time monitoring system has been developed using Wi-Fi communications. The ultimate objective of this study is to develop a wireless smart phone monitoring system of engine for the operator of engine to be able to monitor and control engine status even from the outside of engine room and control room based on this study.