Objectives: Postmenopausal hot flush and sweating is troublesome symptom to most of climacteric women. It is well known that Korean medicine is safe and effective on climacteric symptoms. So this study aims to report the clinical effect of Korean medicine on postmenopausal hot flush and sweating. Methods: The patient received herbal medication, acupuncture, moxibustion, cupping therapy, Gong-jin therapy, and Korean medicine music therapy during hospitalization (about 8 days). Results: Hot flush and sweating was effectively reduced after the treatment. Visual Analogue Scale (VAS) for hot flush and sweating decreased from 9 to 2. Hot flush score decreased from 20 to 8. Area of hot flush and sweating also markedly decreased. Conclusions: This case shows that Korean medicine is effective on climacteric symptoms.