The purpose of this study was to evaluate the applicability of the HSPEXP expert system for the calibration of the Hydrological Simulation Program - Fortran (HSPF) for the study watershed. HSPEXP offers advice to the modeler, suggesting parameter changes that might result in better representation of a river basin and provides explanations supporting the recommended parameter changes. The study watershed, Sancheong, is located within the Nakdong River Basin and having the size of $1,072.4km^2$. Input data for the HSPF model were obtained from the landuse map, digital elevation map, meteorological data and others. Water flow data from 2006 to 2008 were used for calibration and from 2009 to 2010 were for validation. Using the HSPEXP expert system, hydrological parameters were adjusted based on total volume, then low flows, storm flows, and finally seasonal flows. For the calibration and validation period, all the HSPEXP model performance criteria were satisfied.