The present study numerically models the interaction between a regular wave and the roll motion of a rectangular floating structure. In order to simulate two-dimensional incompressible viscous two-phase flow in a numerical wave tank with the rectangular floating structure, the present study used the volume of fluid method based on the finite volume method. The sliding mesh technique is adopted to handle the motion of the rectangular floating structure induced by fluid-structure interaction. The effect of the wave period on the flow, roll motion and forces acting on the structure is examined by considering three different wave periods. The time variations of the wave height and the roll motion of the rectangular structure are in good agreement with experimental results for all wave periods. The present response amplitude operator is in good agreement with experimental results with the linear potential theory. The present numerical results effectively represent the entire process of vortex generation and evolution described by the experimental results. The longer wave period showed a different mechanism of the vortex evolution near each bottom corner of the structure compared to cases of shorter wave periods. In addition, the x-directional and z-directional forces acting on the structure are analyzed.