It is still inadequate for investigating the highly nonlinear and complex mechanical behaviors of single-layer latticed domes by only performing a force-based demand-capacity analysis. The energy-based balance method has been largely accepted for assessing the seismic performance of a structure in recent years. The various factors, such as span-to-rise ratio, joint rigidity and damping model, have a remarkable effect on the load-carrying capacity of a single-layer latticed dome. Therefore, it is necessary to determine the maximum load-carrying capacity of a dome under extreme loading conditions. In this paper, a mechanical model for members of the semi-rigidly jointed single-layer latticed domes, which combines fiber section model with semi-rigid connections, is proposed. The static load-carrying capacity and seismic performance on the single-layer latticed domes are evaluated by means of the mechanical model. In these analyses, different geometric parameters, joint rigidities and roof loads are discussed. The buckling behaviors of members and damage distribution of the structure are presented in detail. The sensitivity of dynamic demand parameters of the structures subjected to strong earthquakes to the damping is analyzed. The results are helpful to have a better understanding of the seismic performance of the single-layer latticed domes.