A new-styrofoam-concrete composite sandwich slab with function of heat insulation is designed. Four full-scale simply supported composite sandwich slabs with different shear connectors are tested. Parameters under study are the thickness of the concrete, the height of profiled steel sheeting, the influence of shear connectors including the steel bars and self-drilling screws. Experimental results showing that four specimens mainly failed in bending failure mode; the shear connectors can limit the longitudinal slippery between the steel profiled sheeting and the concrete effectively and thus guarantee the good composite action and cooperative behavior of two materials. The ultimate sagging bending resistance can be determined based on plastic theory. This new composite sandwich slab has high sagging bending resistance and good ductility. Additionally, these test results help the design and application of this new type of composite sandwich slab.