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서지반출
Cancer Preventive Effects of Whole Cell Type Immunization against Mice Ehrlich Tumors
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  • Cancer Preventive Effects of Whole Cell Type Immunization against Mice Ehrlich Tumors
  • Cancer Preventive Effects of Whole Cell Type Immunization against Mice Ehrlich Tumors
저자명
Aysan. Erhan,Bayrak. Omer Faruk,Aydemir. Esra,Telci. Dilek,Sahin. Fikrettin,Yardimci. Cem,Muslumanoglu. Mahmut
간행물명
Asian Pacific journal of cancer prevention : APJCP
권/호정보
2013년|14권 6호|pp.3515-3519 (5 pages)
발행정보
아시아태평양암예방학회
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정기간행물|ENG|
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기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Background: Effects of whole cell type immunization on mice Ehrlich tumours were evaluated. Materials and Methods: After preliminary study, mice were divided two major groups; $1{ imes}1000$ and $100{ imes}1000$ live Ehrlich cell transferred major groups, each divided into four subgroups (n: 10). Study groups were immunized with Ehrlich cell lysates in 0, 3, 7, $14^{th}$ days and after 30 days of last immunization, live Ehrlich cells were transferred. Mice were observed for six months and evaluated for total and cancer free days. Results: Out of $100{ imes}1000$ cell transferred solid type study group, all study group mean and tumour free periods were statistically longer than control groups. All $1{ imes}1000$ Ehrlich cell transferred study groups survived significantly longer than $100{ imes}1000$ Ehrlich cell transferred groups. Conclusions: Ehrlich mice tumours were prevented and survival prolonged with whole cell type immunization. Effects are related to the number of transferred tumor cells.