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Colorectal Cancer Concealment Predicts a Poor Survival: A Retrospective Study
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  • Colorectal Cancer Concealment Predicts a Poor Survival: A Retrospective Study
  • Colorectal Cancer Concealment Predicts a Poor Survival: A Retrospective Study
저자명
Li. Xiao-Pan,Xie. Zhen-Yu,Fu. Yi-Fei,Yang. Chen,Hao. Li-Peng,Yang. Li-Ming,Zhang. Mei-Yu,Li. Xiao-Li,Feng. Li-Li,Yan. Bei,Sun. Q
간행물명
Asian Pacific journal of cancer prevention : APJCP
권/호정보
2013년|14권 7호|pp.4157-4160 (4 pages)
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아시아태평양암예방학회
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Objectives: Understanding the situation of cancer awareness which doctors give to patients might lead to prognostic prediction in cases of of colorectal cancer (CRC). Methods: Subsets of 10,779 CRC patients were used to screen the risk factors from the Cancer Registry in Pudong New Area in cancer awareness, age, TNM stage, and gender. Survival of the patients was calculated by the Kaplan-Meier method and assessed by Cox regression analysis. The views of cancer awareness in doctors and patients were surveyed by telephone or household. Results: After a median observation time of 1,616 days (ranging from 0 to 4,083 days) of 10,779 available patients, 2,596 of the 4,561 patients with cancer awareness survived, whereas 2,258 of the 5,469 patients without cancer awareness and 406 of the 749 patients without information on cancer awareness died of the disease. All-cause and cancer-specific survival were poorer for the patients without cancer awareness than those with (P < 0.001 for each, log-rank test). Cox multivariate regression analysis showed that cancer concealment cases had significantly lower cancer-specific survival (hazard ratio (HR) = 1.299; 95 % confidence interval (CI): 1.200-1.407)and all-cause survival (HR = 1.324; 95 % CI: 1.227-1.428). Furthermore, attitudes of cancer awareness between doctors and patients were significantly different (P < 0.001). Conclusion: Cancer concealment, not only late-stage tumor and age, is associated with a poor survival of CRC patients.