Recently, the number of disasters has been seriously increasing. The total damages by the natural or man-made disasters during the past years resulted in tremendous fatalities and recovery costs. It is necessary to have efficient emergency evacuation management which is concerned with identifying evacuation route, and the estimation of evacuation and clearance times. An emergency evacuation model is important in identifying critical locations, and developing various evacuation strategies. In that existing evacuation models have focused on route analysis for indoor evacuation, there are only a few models for areawide emergency evacuation analysis. Therefore, we developed a mesoscopic model by using Cube Avenue and performed evacuation simulation, targeting road network in City of Fargo, North Dakota. Consequently, a mesoscopic model developed in this study is used to carry out dynamic analysis using network and input variable of existing travel demand model. The results of this study show that the model is an appropriate tool for areawide emergency evacuation analysis to save time and cost. Henceforth, the results of this study can be applied to develop a disaster evacuation model which can be used for a variety of disaster simulation and evaluation based on scenarios in the local metropolitan area.