Most cases of power transformer failure are caused by physical factors linked to the transient vibrations of multiple 120Hz combinations. In addition, the noise generated in the transformer from this vibration not only directly contributes to the worsening of the work environment but also causes psychological stress, resulting in the worsening of the workers efficiency and of the living environment of the inhabitants around the power plant. Thus, to remedy these problems, the mechanical-excitation forces working on a power transformer were categorized in this study, and the mechanical-damage mechanism was identified through the vibration transfer paths acting on machines or structures. In addition, a study on active noise cancellation in a transformer using the FXLMS algorithm was conducted to develop a system that is capable of multiple-sound/channel control, which resulted in the active noise reduction effect when applied on the field.