The proper occlusal design is one of the most important factors for the long-term success. The purpose of this research is to investigate and define occlusal considerations to reduce failure of implant-supported fixed prostheses. The physiological movement of implants is markedly lower than that of natural teeth and they also lack in occlusal sensitivity. Proper occulsal pattern may be assigned to compensate for the biological disadvantages and occlusal contacts must be formed where the cantilever effect is minimized. Moreover, the long-term success can be assured by reducing early occulsal loading to avoid implant overloading and selecting appropriate occlusion material.