The purpose of this study is to investigate the seismic performance of reinforced concrete (RC) frames strengthened by profiled steel sheet bracing which takes the influence of infill walls into consideration. One-bay, two-story, 1/3 scale two specimens shared same feature of dimensions, one specimen consists only beams and columns; the other one is reinforced by profiled steel sheet bracing with infill walls. Hysteretic curves, envelope curves, stiffness degradation curves and energy dissipation capacities are presented based on test data. Test results indicate that the ultimate load of strengthened specimen has been improved by 225%. The stiffness of reinforced by profiled steel sheet bracing has been increased by 108%. This demonstrates that infill walls and profiled steel sheet bracing enhanced the strength and stiffness distinctly. Energy dissipation has an obvious increase after 12 cycles. This shows that the reinforced specimen is able to bear the lateral load effectively and absorb lots of seismic energy.