Objectives : The purpose of this study is to report the improvement in patients with knee pain by the instrumentality of needle-embedding therapy. Methods : We treated 5 patients who have a disease related with osteoarthitis of the knee by needle-embedding therapy combined with Korean medical treatment. We checked numeric rating scale(NRS) and Western Ontario and McMaster Universities index(WOMAC index). Results : NRS and WOMAC index were decreased at all cases. Conclusions : This study shows needle-embedding therapy has a medical effect when applied on osteoarthritis of the knee.