In this paper two protocols of Wireless Sensor Networks (WSN) are examined through both a simulation and a case study. The simulation was performed with the optimized network (OPNET) simulator while comparing the performance of the Ad-Hoc on demand Distance Vector (AODV) and the Dynamic Source Routing (DSR) protocols. This is compared and shown with real-world measurement of deflection from eight wireless sensor nodes. The wireless sensor response results were compared with accelerometer sensors for validation purposes. It was found that although the computer simulation suggests the AODV protocol is more accurate, in the case study no distinct difference was found. However, it was shown that AODV is still more beneficial in the field as it has a longer battery life enabling longer surveying times. This is a significant finding as a large factor in determining the use of wireless network sensors as a method of assessing structural response has been their short battery life. Thus if protocols which enhance battery life, such as the AODV protocol, are employed it may be possible in the future to couple wireless networks with solar power extending their monitoring periods.