Fatigue and wear in wheels is often due to the forces and loading. These certainly have fundamental effects on reducing the wheel life and increasing the costs related to repairing and maintenance. Modeling and stress analysis of a wheel sample existing in the Iranian fleet have been performed in its contact with U33 and UIC60 rails. The results have been reviewed and analyzed in elastic and elastic-plastic phase and under static (railcar weight) and quasi static loads. Moreover, effects of wheel diameter, axle load, wheel material, rail type are analyzed.