An implantable CPW fed monopole antenna embedded into human tissue is proposed for ISM band biomedical applications. The proposed antenna is made compatible for implantation by embedding it in an alumina ceramic substrate (${Box}_r=9.8$ and thickness=0.65 mm). The proposed antenna covers the ISM band of 2.45 GHz. The radiation parameters, such as return loss, E-Plane, H-Plane, are measured and analyzed, using the method of moments. The proposed antenna has substantial merits over other implanted antennas, like low profile, miniaturization, lower return loss, and better impedance matching and high gain.