This research presents a method for the initial structural design of a multi-megawatt wind turbine blade. The structural data for a 2-MW blade were applied as the blade structural characteristic data of the reference blade. Tenkinds of blade models were newly designed by replacing the spar cap axial GRRP with a GFRP and CFRP These terms should be defined. at different orientations. The axial stiffness coefficients of the newly designed models were made equal to the coefficient of the reference blade. The required numbers of layers in each section of blades were calculated, and the lay-up designs were based on these numbers. Verification results showed that the design method that used the structural data of the reference blade was appropriate for the initial structural design of a wind turbine blade.