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Viscoelastic Behavior of a Single Collagen Molecule
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  • Viscoelastic Behavior of a Single Collagen Molecule
  • Viscoelastic Behavior of a Single Collagen Molecule
저자명
Yoon. Young June,Cho. Kang-Hee,Han. Seog-Young
간행물명
International journal of precision engineering and manufacturing
권/호정보
2014년|15권 4호|pp.783-786 (4 pages)
발행정보
한국정밀공학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Collagen represents the most abundant protein in the human body and plays an important role in connective tissues. Here, molecular dynamics simulation was performed to assess tension of a single collagen molecule, and stress-strain curves were obtained. In total, two regions (termed regions I and II) in the curve were displayed. In region I, as the pulling velocity increased from $0.5{AA}/ps$ to $5{AA}/ps$, the effective elastic modulus increased from 18.613 GPa to 27.632 GPa when water surrounded a single collagen molecule and increased from 15.308 GPa to 17.665 GPa when no water was involved. Conversely, in region II, effective modulus did not significantly change in response to changes in pulling velocity for both scenarios. We concluded that the viscoelastic behavior observed in region I corresponded to the uncurling of the collagen triple-helix. Water molecules likely play an important role in this viscoelastic behavior.