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Risk Factors for Appendiceal Metastasis with Epithelial Ovarian Cancer
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  • Risk Factors for Appendiceal Metastasis with Epithelial Ovarian Cancer
  • Risk Factors for Appendiceal Metastasis with Epithelial Ovarian Cancer
저자명
Kokanali. Mahmut Kuntay,Guzel. Ali Irfan,Erkilinc. Selcuk,Tokmak. Aytekin,Topcu. Hasan Onur,Gungor. Tayfun
간행물명
Asian Pacific journal of cancer prevention : APJCP
권/호정보
2014년|15권 6호|pp.2689-2692 (4 pages)
발행정보
아시아태평양암예방학회
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정기간행물|ENG|
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기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Purpose: To investigate the risk factors for appendiceal metastasis of epithelial ovarian cancer and compare findings with the previous studies. Materials and Methods: One hundred and thirty-four patients with epithelial ovarian cancer were assessed in this study. All of them had undergone a surgical procedure including appendectomy. Of these, 21 (15.7%) patients who had appendiceal metastasis were analyzed as the case group and the patients with no metastasis were the controls, compared according to stage, grade, histology of tumor, preoperative Ca125 levels, presence of ascites, peritoneal cytology, diameter and site of tumor considered as risk factors. Results: We found statistically significant differences between the groups in terms of stage, grade, right-sided tumor location, presence of ascites, diameter of tumor${geq}10cm$ and positive peritoneal cytology (p<0.05). In the logistic regression model, stage, grade, presence of ascites, right-sided location and diameter of tumor were independent risk factors. ROC curve analysis showed that stage, grade and diameter of the tumor were discriminative factors for appendiceal metastasis. Conclusions: In epithelial ovarian cancer, stage, grade, presence of ascites, right-sided location and large tumor size have importance for estimation of risk of appendiceal metastasis. As we compare our findings with previous studies, there is no definite recommendation for the risk factors of appendiceal metastasis in epithelial ovarian cancer and more studies are needed.