The purpose of this study was to analyze spectral versus cepstral measurements in esophageal speakers. The comparison between the measurements in thirteen male esophageal speakers was compared with the control group of thirteen normal speakers using the sustained vowel /a/. The main results can be summarized as below: (a) the CPP and L/H ratio of the esophageal group were significantly lower than those of the control group (b) the CPP was significantly correlated with the spectral parameters such as jitter, shimmer, NHR and VTI, and (c) the ROC analysis showed that the threshold of 10.25dB for the CPP achieved a good classification for esophageal speakers, with 100% perfect sensitivity and specificity. Thus, it was known that cepstral-based acoustic measures such as CPP, may be more reliable predictors than other spectral-based acoustic measures such as jitter and shimmer. And it was found that cepstral-based acoustic measures were effective in distinguishing esophageal voice quality from normal voice quality. This research will contribute to establishing a baseline related to speech characteristics in voice rehabilitation with laryngectomees.