Materials that can be use in CAD/CAM are composite, ceramic, hybrid and metal. Among the available materials, monolithic ceramic technique which is the manufacturing technique using one type of the materials is mainly used in a dental office. It is the technique where final tooth-shaped prostheses are made from the material block and used after polishing or applying heat and that does not require traditional ceramic build-up process. Although shot of esthetic quality, because manufactured within 1 hour the monolithic ceramic technique has advantages such as that treatment can be completed in one day and in one time visit, that stability of the material is high because there are low possibility of distort by not melting and phase transformation, and that it can be easily worked in the office with computer assisted devices. We classified the materials that can be used in this technique based on their generations from clinical stand point.