In the present study, the characteristics of laser ultrasound in the ablation regime are investigated using simulations and experiments. The laser ultrasonic technique has been recognized as a noncontact method in the field of nondestructive tests (NDTs). In hostile environments (such as hot temperatures), this method has various advantages over the conventional contact ultrasonic method. In particular, in the ablation regime, the laser ultrasonic technique is suitable for inspecting internal defects because of the high amplitude and directivity of the longitudinal wave. In this paper, a simulation model for laser ultrasound in the ablation regime was developed. This model was subsequently applied to a defective specimen using the B-scan method to locate defects. Finally, we performed an experimental test to verify the simulation results. Consequently, the simulation demonstrated good agreement with the experimental test.