The extraction of lip region is essential to Lip Reading, which is a field of image processing to get some meaningful information by the analysis of lip movement from human face image. Many conventional methods to extract lip region are proposed. One is getting the position of lip by using geometric face structure. The other discriminates lip and skin regions by using color information only. The former is more complex than the latter, however it can analyze black and white image also. The latter is very simple compared to the former, however it is very difficult to discriminate lip and skin regions because of close similarity between these two regions. And also, the accuracy is relatively low compared to the former. Conventional analysis of color coordinate systems are mostly based on specific extraction scheme for lip regions rather than coordinate system itself. In this paper, the method for selection of effective color coordinate system and chromaticity transformation to discriminate these two lip and skin region are proposed.