Bio fuel oil combustion experiments were successfully demonstrated at the 75 MWe oil-fired power plant without major equipment retrofit and 100% bio-fuel oil combustion was possible without big problems. The experimental data error correction was conducted and numerical model-based analysis technique was applied for the evaluation of the results. Incase of bio fuel oil combustion, heat absorption of radiative heat transfer section was reduced while convection section has opposite trend. The furnace exit gas temperature tends to rise slightly. Environment emissions such as NOx and SOx concentrations showed a tendency to decrease during the bio fuel oil combustion period. On the other hand, boiler efficiency was slightly underestimated.