River bank filtration techniques seek to improve river water quality via natural processes occurring when river water is induced to a river bank. When water is pumped from multiple wells, phenomenon known as well interference affect pumping rates. Pumping wells of a bank filtration facility are connected by pipelines. In theses cases well interference is caused not only by groundwater drawdown but also by pipe headloss which depend on flow rates. In this work a comprehensive analytical method which handles groundwater flow and pipe flow is used to evaluate interferences and ratios of river water in pumping wells. A realistic case was used as an example.