Cyber-Physical Systems(CPS) that mostly provides safety-critical and mission-critical services requires high reliability, so that system testing is an essential and important process. Hardware-In-the-Loop Simulation(HILS) is one of the extensively used techniques for testing hardware systems. However, most conventional HILS has problems that it is difficult to support a distributed operating environment and to reuse a HILS platform. In this paper, we introduce EcoHILS(ETRI CPS Open Human-Interactive hardware-in-the-Loop Simulator) in order to test CPS effectively. Moreover, feasibility tests and performance tests of EcoHILS are performed to confirm its effectiveness.