This study was conducted to analyze the satisfaction level that students in physical therapy departments have with their major after they enter college; it also aimed to present the factors that affect that satisfaction. With regard to satisfaction in relation to general characteristics, no significant difference in satisfaction was shown between the two genders or among the times of selection of the department. Significant differences in satisfaction with the department were found for high school courses, school systems, grades, and the influences on the selection of the department. The variables that significantly affected satisfaction with the department were: satisfaction with perception, satisfaction with curricula, general satisfaction, and satisfaction with relationships. In particular, satisfaction with perception showed the highest standardized regression coefficient value for satisfaction with the department. Based on the results of this study, to enhance the satisfaction levels of students in physical therapy departments, interest in physical therapy should be drawn from the students based on social perception and high level educational environments, and the relationship between the processors and the students should be improved.