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서지반출
Functional Roles of Long Non-coding RNA in Human Breast Cancer
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  • Functional Roles of Long Non-coding RNA in Human Breast Cancer
  • Functional Roles of Long Non-coding RNA in Human Breast Cancer
저자명
Ye. Ni,Wang. Bin,Quan. Zi-Fang,Cao. San-Jie,Wen. Xin-Tian,Huang. Yong,Huang. Xiao-Bo,Wu. Rui,Ma. Xiao-Ping,Yan. Qi-Gui
간행물명
Asian Pacific journal of cancer prevention : APJCP
권/호정보
2014년|15권 15호|pp.5993-5997 (5 pages)
발행정보
아시아태평양암예방학회
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

The discovery of long noncoding RNA (LncRNA) changes our view of transcriptional and posttranscriptional regulation of gene expression. With application of new research techniques such as high-throughput sequencing, the biological functions of LncRNAs are gradually becoming to be understood. Multiple studies have shown that LncRNAs serve as carcinogenic factors or tumor suppressors in breast cancer with abnormal expression, prompts the question of whether they have potential value in predicting the stages and survival rate of breast cancer patients, and also as therapeutic targets. Focusing on the latest research data, this review mainly summarizes the tumorigenic mechanisms of certain LncRNAs in breast cancer, in order to provide a theoretical basis for finding safer, more effective treatment of breast cancer at the LncRNA molecular level.