This major purpose of this study is to examine factors influencing the attitude toward News Feed advertising in Facebook. For this purpose, this study posited seven determinants including informativeness, entertainment, irritation, trust, individualization, incentive and privacy concern, which can have influences on the attitude toward News Feed Advertising. and this research tests the relationships between these seven determinants and the attitude toward News Feed Advertising. An online survey was administrated to collect data and hierarchical regression analyses were employed for data analysis. The results showed that infortainment as a new combined factor of informativeness and entertainment, trust, individualization have significantly positive influences on the attitude toward News Feed advertising in Facebook. It was also shown that the moderating effect of involvement on the relationship between irritation and the attitude. The results in this study implied that it is needed to reinforce the attributes of advertising including infortainment, trust and individualization to boost the effects of News Feed advertising in Facebook on consumers.