The poor seismic performance of reinforced concrete buildings during the latest earthquakes has become a serious issue in the building industry in Turkey. This case, designing new buildings without structural irregularities against earthquake loads reveals to be quite significant. This study mainly is focused on the effects of different torsional irregularities on construction costs and earthquakes performance of reinforced concrete buildings. In that respect, structural torsional irregularities are investigated based on the Turkish Earthquake Code. The study consists of major eight main parametric models. In this models consist of totally 49 models together with the variations in the number of storey. With this purpose, the earthquake performances and construction costs (especially steel quantities) of reinforced concrete buildings which having different structural torsional irregularities were obtained with the help of Sta4-CAD program. Each model has been analyzed by both the methods of equivalent earthquake loading and dynamic analysis. The obtained results reveal that the model-1 which has lower torsional irregularity coefficient shows the best earthquake performance owing to its regular plan geometry. Also, economical comparisons on costs of the torsional irregularity are performed, and results-recommendations are given.