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서지반출
Clinico-Morphological Profile and Receptor Status in Breast Cancer Patients in a South Indian Institution
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  • Clinico-Morphological Profile and Receptor Status in Breast Cancer Patients in a South Indian Institution
  • Clinico-Morphological Profile and Receptor Status in Breast Cancer Patients in a South Indian Institution
저자명
Ghosh. Saptarshi,Sarkar. Shreyasee,Simhareddy. Samara,Kotne. Sivasankar,Rao. Pammidimukkala Bramh Ananda,Turlapati. Satya Prakas
간행물명
Asian Pacific journal of cancer prevention : APJCP
권/호정보
2014년|15권 18호|pp.7839-7842 (4 pages)
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아시아태평양암예방학회
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정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Background: Breast cancer is the most common malignancy in women worldwide and the second most common cancer in females in India. Receptor status may be important for survival. Objective: To analyse and correlate the clinical and morphological parameters with receptor status in breast carcinoma patients in a tertiary care institution in Southern India. Materials and Methods: This retrospective study involved 320 patients of breast cancer diagnosed in an oncology hospital over a period of $3^{1/2}$ years. Data was analysed using SPSS Version 21. Results: Some 60.6% patients with breast carcinomas belonged to the age group of 40 to 60 years. The most common histological type was infiltrating ductal carcinoma, not otherwise specified, accounting for 84.4% of patients. On immunohistochemistry, estrogen receptor (ER) and progesterone receptor (PR) were expressed in 56.3% and 53.1% of cases, respectively. Conclusions: Breast cancers in India, a developing country, occur in younger women and tend to be more aggressive with lower rates of ER and PR expression and higher histological tumor grades. Both ER and PR status of the tumors had significant associations with the patient age, pathological TNM stage and histological tumor grade.