At SAC 2004, Junod and Vaudenay designed the FOX family based on the Lai-Massey scheme. They noted that it was impossible to find any useful differential characteristic or linear trail after 8 rounds of FOX64 or FOX128. In this paper, we provide the lower bound of differentially active S-boxes in consecutive rounds of the Lai-Massey scheme that has SPS as its F-function, and we propose the necessary conditions for the reachability of the lower bound. We demonstrate that similar results can be obtained with respect to the lower bound of linearly active S-boxes by proving the duality in the Lai-Massey scheme. Finally, we apply these results to FOX64 and FOX128 and prove that it is impossible to find any useful differential characteristics or linear trail after 6 rounds of FOX64. We provide a more precise security bound for FOX128.