The purpose of this study examined the differences in work-family spillover process and domains in dual-earner couples with children, using a multidimensional measure of work-family spillover. The subjects of this study were 285 working couples with children. The research tool was questionnaires which consisted of general characteristics of the subjects and multidimensional measure of work-family spillover scale. For data analysis, factor analysis, Cronbach ${alpha}$, t-test, and paired t-test were performed. Based on analysis of data using factor analysis, three-distinct work-family spillover process can be measured for both wife and husband, time interference, psychological distraction, and energy depletion and the multidimensional measure of work-family spillover is able to validly assess different domains of family life into which spillover occurs. The main results of this study were as following: First, there were significant differences in work-family spillover process according to sex. In work${ ightarrow}$family spillover, male more experienced negative time interference than female, on the other hand, in family${ ightarrow}$work spillover, female more experienced negative energy depletion than male. Second, there were significant differences in domains which work-family spillover occurs according to sex. Male more experienced negative work${ ightarrow}$family spillover than female in marital relations and parent-child relations domains while female more experienced negative family${ ightarrow}$work spillover than male in parent-child relations and home management domains. Third, there were significant differences between wife and husband in work-family spillover process. In work${ ightarrow}$family spillover, husband more experienced negative time interference than wife, on the other hand, in family${ ightarrow}$work spillover, wife more experienced negative energy depletion than husbands. Forth, there were significant differences between wife and husband in domains which work-family spillover occurs. Male more experienced negative work${ ightarrow}$family spillover than female in marital relations, parent-child relations, and leisure life domains. And while husband more experienced negative family${ ightarrow}$work spillover than wife in parent-child relations, wife more experienced negative family${ ightarrow}$work spillover than husband in home management domains.