Many regions around the world are vulnerable to rainfall-induced slope failures. A variety of methods have been proposed for revealing the mechanism of slope failure initiation. Current analysis methods, however, do not consider the effects of non-homogeneous soil profiles and variable hydraulic responses on rainfall-induced slope failures. In this study, probabilistic stability analyses were conducted for weathered residual soil slopes with different soil thickness overlying impermeable bedrock to study the rainfall-induced failure mechanisms depending on the soil thickness. A series of seepage and stability analyses of an infinite slope based on one-dimensional random fields were performed to consider the effects of uncertainty due to the spatial heterogeneity of hydraulic conductivity on the failure of unsaturated slopes due to rainfall infiltration. The results showed that a probabilistic framework can be used to efficiently consider various failure patterns caused by spatial variability of hydraulic conductivity in rainfall infiltration assessment for a infinite slope.