The realistic cases causing severe core damage should be analyzed and arranged systematically for preparing an accident management of the specific nuclear power plant. The objective of this paper is to establish basic technical information for reactor safety and reactor building integrity management strategies in CANDU reactor severe accident. For the development of severe accident management strategies, plant specific features and behaviors must be studied by detailed analysis works. This analysis scope will serve to cover overall methods and analyzing results to understand the reactor building integrity status in the most likely severe accident sequences that could occur at CANDU reactor. Also analysis results could help prevent or mitigate severe accidents for the identification of any plant specific vulnerabilities to severe accidents using the probabilistic safety assessment (PSA) quantified results.