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서지반출
Association of Risk of Gastric Cancer and Consumption of Tobacco, Alcohol and Tea in the Chinese Population
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  • Association of Risk of Gastric Cancer and Consumption of Tobacco, Alcohol and Tea in the Chinese Population
  • Association of Risk of Gastric Cancer and Consumption of Tobacco, Alcohol and Tea in the Chinese Population
저자명
Tong. Gui-Xian,Liang. Han,Chai. Jing,Cheng. Jing,Feng. Rui,Chen. Peng-Lai,Geng. Qing-Qing,Shen. Xing-Rong,Wang. De-Bin
간행물명
Asian Pacific journal of cancer prevention : APJCP
권/호정보
2014년|15권 20호|pp.8765-8774 (10 pages)
발행정보
아시아태평양암예방학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

This study aimed at summarizing epidemiological research findings on associations between tobacco, alcohol and tea consumption and risk of gastric cancer (GC) in the Chinese population. The review searched PubMed, Embase, China National Knowledge Infrastructure (CNKI) and China Biology Medicine (CBM) databases and reference lists of review papers for all studies published in English or Chinese languages. Information extracted, via two independent researchers, from retrieved articles included first author, year of publication, study design, sample size, source of controls and adjusted odds ratio (OR) or relative risk (RR) with the corresponding 95% confidence intervals (CIs) for each category. Statistical analyses used software STATA version 12.0. The systematic search found 89 articles containing 25,821 GC cases and 135,298 non-cases. The overall random effects in terms of pooled OR and 95%CI for tobacco, alcohol and tea consumption were 1.62 (95%CI: 1.50-1.74), 1.57 (95%CI: 1.41-1.76) and 0.67 (95%CI: 0.59-0.76) respectively; while the heterogeneity among included studies ranged from 80.1% to 87.5%. The majority of subgroup analyses revealed consistent results with the overall analyses. All three behavioral factors showed statistically significant dose-dependent effects on GC (P<0.05). The study revealed that tobacco smoking and alcohol drinking were associated with over 1/2 added risk of GC, while tea drinking conferred about 1/3 lower risk of GC in the Chinese population. However, these results should be interpreted with caution given the fact that most of the included studies were based on a retrospective design and heterogeneity among studies was relatively high.