PS-D2EHPA beads were prepared by immobilizing di-2-ethylhexyl-phosphoric acid (D2EHPA) with polysulfone (PSf). The removal experiments of Cu(II) and Pb(II) by the prepared PS-D2EHPA beads were conducted batchwise. The removal efficiency of Cu(II) and Pb(II) by PS-D2EHPA beads was increased with increasing pH of solution. The removal rate of Cu(II) and Pb(II) was well described by the pseudo-second-order kinetic model. The maximum removal capacity of Cu(II) and Pb(II) obtained from Langmuir isotherm were 2.58 mg/g and 12.63 mg/g, respectively. External mass transfer coefficients for the removal of Cu(II) and Pb(II) by PS-D2EHPA beads were obtained $0.61{ imes}10^{-2}{sim}5.87{ imes}10^{-2}/min$ and $1.55{ imes}10^{-2}{sim}8.53{ imes}10^{-2}/min$, respectively and diffusion coefficients were obtained $1.32{ imes}10^{-4}{sim}3.98{ imes}10^{-4}cm^2/min$ and $1.80{ imes}10^{-4}{sim}2.28{ imes}10^{-4}cm^2/min$, respectively.