The study sought to assess Early Childhood Education Pre-service Teachers’ Pedagogical Content Knowledge in Teaching Psychosocial skills across the kindergarten curriculum in Ghana. A mixed method approach was used. The study comprised 123 conveniently selected regular final year preservice teachers pursuing a degree in early childhood education in a public university in Ghana, who have completed their internship programme. Questionnaires were administered after which five students were selected for a focused group discussion. Data were analysed using means, standard deviation and narratives. The study showed that Pre-service teachers had enough knowledge in achieving two goals of the KG curriculum and were also more familiar with the use of fieldtrips and demonstration. They also had enough knowledge in the use of observation and conversation among others. A thorough examination of the KG curriculum by pre-service teachers during pre and post internship was recommended.