This study aims to investigate whether participation motivation(intrinsic motivation, extrinsic motivation) and teaching presence predict learning outcomes(satisfaction, achievement, learning persistence) in the lifelong learning context. Also, this study examines the mediating effects of learner satisfaction between predictors and learning outcomes. In order to test the hypotheses of this study, the data from 87 respondents who participated in a lifelong education program were analyzed using regression analysis. The results of the study indicated that teaching presence significantly predicted learning outcomes, that is, satisfaction, achievement, and learning persistence. However, participation motivation was not significantly correlated with all these learning outcome variables. Also, satisfaction had significant mediating effects between teaching presence and achievement, and between teaching presence and learning persistence. Based on the results of this study, implications were provided: Further understanding on learners’ motivation in lifelong learning settings are required. Also further research investigating other predicting variables should follow in order to shed lights on the learning outcomes of lifelong learning.