It has been described that the pelvic and adjoining viscera are innervated by sympathetic fibers from the hypogastric nerve. However, the mode of action of the hypogastric nerve fibers on the organs is not fully understood. The present paper reviewed the results of investigations on the mode of action of the hypogastric nerve with an emphasis of the experimental results obtained by the author and author s associates. The evidences clarified that the hypogastric fibers to the distal colon are cholinergic, whereas the fibers to the uterus, seminal vesicle, seminal duct and urinary bladder are adrenergic.
