Hypothalamus is one of the most important center regulating voluntary and involuntary function of the body. We studied on the blood glucose and eosinophilic responses induced by electrical hypothalamic stimulation using stereotaxic apparatus. Blood glucose was measured according to Somogyi Nelson method and circulating eosinophil was counted with Hinkleman Stain. For the histological confirmation of electrode placement frozen sections were cut along electrode tract and stained with Hematoxylin-Eosin. The results obtained were as follows: 1. Anterior hypothalamic stimulation mostly leads to hypoglycemia but in some cases lead to hyperglycemia. 2. Hypothalamic stimulation leads to eosinopenia in majority cases. 3. There is no relationship between eosinopenia and hyperglycemia. 4. It appears that sympathetic and pararympathetic areas are not separate part but it coincides each other.