Epilepsy, a chronic illness, may cause high levels of psychosocial difficulties for all family members, including stigmatization, stress, marital problems, and restriction of social activities. Through the collection and analysis of survey data from 141 parents seeking medical treatment for their epileptic children, this study investigated the influence of family strength on the adaptiveness of the families. Multiple regression analysis demonstrated that 74% of family adaptation could be explained by family stress, family coherence, and family hardiness. In addition, family coherence and family hardiness each had a significant positive effect on family adaptation. The study’s findings suggest that strength-based interventions, focused on increasing family coherence and hardiness, can be effective in improving the adaptation of families with epileptic children.