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석류ㆍ참다래 혼합추출물의 체지방 감소에 대한 유효성 및 안전성을 평가하기 위한 8주, 무작위 배정, 이중눈가림, 위약-대조 인체적용시험
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  • 석류ㆍ참다래 혼합추출물의 체지방 감소에 대한 유효성 및 안전성을 평가하기 위한 8주, 무작위 배정, 이중눈가림, 위약-대조 인체적용시험
  • A 8-Week, Randomized, Double-Blind, Placebo-Controlled Human Trial to Evaluate the Efficacy and Safety of Punica granatum L.ㆍ Actinidia chinensis Planch. Mixed Extract on Body Fat
저자명
최진봉(Jin bong Choi),이지은(Ji eun Lee),도윤경(Yun kyoung Do)
간행물명
대한한방비만학회지KCI
권/호정보
2017년|17권 2호|pp.87-95 (9 pages)
발행정보
한방비만학회|한국
파일정보
정기간행물|KOR|
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영문초록

Objectives: This study was conducted to evaluate efficacy and safety of Punica granatum L.ㆍ Actinidia chinensis Planch. mixed extract on body fat.\nMethods: Thirty women were recruited (25 kg/m2≤body mass index [BMI]≤29.9 kg/m2) (19 yr≤ age≤38 yr) and randomized to receive Punica granatum L.ㆍActinidia chinensis Planch. mixed extract or placebo for 8 weeks. During the test, they visited four times including screening. Body fat mass, body fat rate, anthropometric dimensions at waist and hip, waist-hip ratio, total cholesterol, triglyceride, low density lipoprotein-cholesterol (LDL-C), and high density lipoprotein-cholesterol (HDL-C) were measured at screening and 8 weeks after screening. Adverse reaction were also checked each visit.\nResults: There were no significant differences in all index. But when divide experimental group by BMI index, age, and compliance, less than BMI 27 kg/m2 group decreased body weight, body fat mass and more than BMI 27 kg/m2 group also decreased body weight, body fat mass and waist circumference. Less than age 30 years group showed decline of waist circumference, fat free rate and T-cholesterol and more than age 30 years group showed decline of fat free mass. Group with compliance more than 95% was decreased BMI, fat free mass, and hip circumference.\nConclusions: There was no significant efficacy as compared with placebo group, but as divide experimental group according to BMI index, age, compliance, mixed extract might be effective to reduce obesity index.

목차

서 론\n대상 및 방법\n결 과\n고 찰\n결 론\n감사의 글\nReferences

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