Localized fat and cellulite have not only esthetic but health problem, they are treated by surgical or non-surgical method. There are elecro-acupuncture, ultrasound, radio frequency, endermologie, mesotherapy, and carbon dioxide therapy in prevalent non-surgical treatments. We reviewed the studies on them to analyze their scientific evidence. The studies are not many. They reported good results of circumference loss or appearance improvement or histologic change but most of them have poor study design. Before marketing or using these modalities, it is critical to evaluate to their effectiveness through strict and scientific clinical trials.