Objective : The purpose of this study is to investigate how to use the Quality of Life(QoL) of obesity and to study the report cases which measure QoL on obesity. Method : This study investigate the definition of Health-related Quality of Life(HRQoL), the measurement of Health-related Quality of Life, and the papers of Health-related Quality of Life on obesity through the books and medicine journals of HRQoL and obesity. Conclusions : 1. The QoL includes role functional ability, the degree and quality of social and community interaction, psychological state, somatic feeling, and life satisfaction than personal health and social well-being. 2. The investigator needs to evaluate the reliability, validity and sensitivity of the scale, and the appropriateness of the instrument for the target population When he decides measurement. 3. The investigator have the well-drilled supporter or himself managed the data and study population to prevent missing data. 4. The investigator should decide which is needed on obesity a obesity-specific or broad-ranging instrument, or both.