Purpose: To evaluate the educational effectiveness of practice-based program for procedural skills at Kangwon National University College of Medicine. Methods: In 2005, we conducted the training program composed of 19 procedural skills for third-year medical students during their first semester clerkship. The 14-week training used simulation models and was held for 3 hours per week, one hour for didactic session and 2 hours for practical exercise. A lecture was given only for wound dressing. OSCE, consisting of four 5-minute stations, was administered to analyze the students achievement. 53 third-year students were given a survey following skills training and OSCE. Results: Most students reported that the practice-based program was interesting and helpful in learning procedural skills. Students preferred practice to didactic medium. Students were satisfied with the faculty s instruction, but suggested that the training should be providedprior to clerkship. OSCE had an overall reliability coefficient (Cronbach s alpha) of 0.78. The mean score in the dressing case was lower than those in other cases. Conclusion: The practice-based program for procedural skills was effective in motivating students learning as well as improving theirtechnical skills. Self-directed exercises and appropriate feedback are more effective training tools than lectures.