Purpose: Cardiopulmonary bypass (CPB) is one of the most fundamental and important subjects in cardiovascular surgery. Thus, it is insufficient to understand CPB through only traditional education methods as a comprehensive knowledge based on anatomy and physiology of the circulating system and surgical techniques is essential. The aim of this study was to develop a multimedia CPB　teaching program for a more rewarding learning experience. Methods: Among all teaching materials, text and picture-based lectures, movies on surgical procedures, and animations were chosen to be included in the teaching programs. Firstly, we made lecture notes and a powerpoint lecture with narration. Secondly, we made and edited movie files on surgical procedures, and incorporated sound in the movies. Thirdly, we developed animation files including all CPB procedures using flash 5.0. Finally we made a CD ROM and a web page for CPB and other basic surgical techniques. A basic wurgical procedures Self-test was also included. Questionnaires were given to medical students to evaluate the effectiveness and the ease of use of this program. Results: The developed CPB educational program was distributed in a CD-ROM. An internet homepage (http://surgery.chungbuk.ac.kr) for basic surgical procedures was constructed with the multimedia CPB lecture. The results of the questionnaires were positive, Proving the improved understanding of CPB. Conclusion: This multimedia education program on CPB not only can help medical students to easily understand the structures and principles involved in CPB, but also give indirect experience of this surgical procedure.