The purpose of this study was for providing a basic resource to prevent risk factors of metabolic syndrome and have interventions throughout analyzing the factors affecting and identifying the features of the targets who were related with the metabolic syndrome prevalence rate among the middle-aged women who are living in rural area of Gyeongsang province. The study targets were over 30 years old of the middle-aged women who are in rural area of Gyeongsang province that registered in National Cancer Center community basic cohort from 2000 to 2010 and were analyzed χ²-test, t-test, logistic regression analysis using SPSS 23.0 program. According to the study result, there were significant differences with respect to height(t=4.21, p<.001), weight(t=5.13, p<.001), body mass index(t=3.66, p<.001), systolic blood pressure(t=-2.16, p=.031), diastolic blood pressure(t=-3.27, p=.001), fasting glucose(t=-2.45, p=.014) and triglyceride(t=3.23, p=.001) between 2000~2005 and 2006~2010. The risk factors of metabolic syndrome showed its significantly in irregular exercise(Odds ration(OR)=1.67) group, was low to higher education group(OR=.51) from 2006 to 2010, and irregular meals(OR=1.21) and age(OR=3.00) group from 2000 to 2005. Based on this research result, we need to provide the information, education, health control program that related to diet, exercise, academic background, age for the rural area middle-aged women and need to study for reducing the metabolic syndrome prevalence rate continuously.