The present paper describes 3 clinical cases in which the orthodontic, treatment was effected by the Bioprogressive therapy following the extraction of the upper and lower first premolars. What is most noteworthy in the present treatment is the use of a systems approach to diagnosis and treatment by the application of the visual treatment objective in planning treatment, evaluating anchorage and monitoring results, and the rest being performed routinely by Bioprogressive mechanism. The result achieved by this method is very favorable and the efficiency of the Bioprogressive therapy is quite satisfactory.