The purpose of this study was to investigated Oral health Knowledge and practice and oral care devices usage in health and non Health Related Majors, The subjects were 158 students in health and non Health Related Majors from september, to december 2015. The data were analyzed using SPSS 21.0 for frequency analysis, χ2-test, Pearson s correlation analysis. In the case of toothbrush selection method, 80.5% of the health department responded that they knew toothbrush selection method, and the ratio of respondents who knew toothbrush selection method was higher in health department than non – health department. Knowledge and behavior of dental health according to the series were higher in the health department than in the non - health department. The association between oral health knowledge and behavior is statistically significant in knowledge and behavior based on Pearson correlation analysis Therefore, university students need to improve their oral health, structuring environment where information about oral health is reached out easily.